ISO 21427-2-2006 水质.通过测量微核诱导评估生物毒性.第2部分:使用细胞链V79型混合种群法

标准号：ISO 21427-2-2006
中文标准名称：水质.通过测量微核诱导评估生物毒性.第2部分:使用细胞链V79型混合种群法
英文标准名称：Water quality - Evaluation of genotoxicity by measurement of the induction of micronuclei - Part 2: Mixed population method using the cell line V79
标准类型：C51;Z16
发布日期：1999/12/31 12:00:00
实施日期：1999/12/31 12:00:00
中国标准分类号：C51;Z16
国际标准分类号：13.060.70
引用标准：ISO 5667-16
适用范围： This part of ISO 21427 specifies a method for the determination of genotoxicity of water and waste water using a mammalian in vitro test which detects damage, induced by water-soluble substances, to the chromosomes or the mitotic apparatus of V79 cells from the Chinese hamster. The micronucleus test allows the identification of substances that cause cytogenetic damage which results in the formation of micronuclei containing lagging chromosome fragments and/or whole chromosomes. The assay is based on the increase in the frequency of micronucleated cells after incubation with and without metabolic activation.