BS EN 12682-1998 生物技术.应用于环境的改良有机体.通过分析遗传改良的功能表达指导改良遗传有机体特性

标准号：BS EN 12682-1998
中文标准名称：生物技术.应用于环境的改良有机体.通过分析遗传改良的功能表达指导改良遗传有机体特性
英文标准名称：Biotechnology - Modified organisms for application in the environment - Guidance for the characterization of the genetically modified organism by analysis of the functional expression of the genomic modification
标准类型：C04
发布日期：1998/12/15 12:00:00
实施日期：1998/12/15 12:00:00
中国标准分类号：C04
国际标准分类号：07.080
适用范围：This European Standard provides guidance on the design and execution of experiments for the analysis of the functional expression of the genomic modification. It gives criteria for the set-up of an experimental design and the determination of the validity of its execution. The main factors influencing the specificity, reliability and limits of detection for an analysis are given for the following categories of experiments: —analysis of the expression of a genomic modification within GMOs (or clones of) or any specified part of them, including its response to internal (developmental stage, growth, organ or tissue location) and external factors (temperature, humidity, pH, other); —establishment of identity of a desired product resulting from the expression of a genomic modification in comparison with a reference; —characterization of the novel trait(s) of a GMO. This European Standard does not cover procedures for the analysis of pleiotropic effects of a genomic modification or the act of generating the GMO (e.g. somaclonal variation) on the phenotype of modified organisms, which cannot be predicted from the knowledge of the type of the genomic modification. However, the principles stated in this European Standard are applicable for the execution of any analysis of gene functions.